Port Salerno is accessible via the Florida Turnpike, i95 and US1. It is located along A1A between Stuart to the north and Hobe Sound to the south. It is part of Martin County, located north of Palm Beach County.
Take I95 to the Stuart exit, take a right on Cove Road, a left on A1A and you will see Port Salerno Historic Waterfront District to the right.
From the FL Turnpike: Take the Stuart exit, travel to Stuart via Kanner Highway. Take a right on US1, a left on Salerno Rd and you will see the port Salerno Historic Waterfront District directly across A1A.